Beilstein J. Org. Chem.2018,14, 1980–1993, doi:10.3762/bjoc.14.173
attention to the synthesis of host molecules with high affinity to biologically important anions [1][2][3][4][5]. Among these anions, nucleotiderecognition and sensing represents an especially important research area due to the great biological significance of these anions. Adenine-containing nucleotides
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Graphical Abstract
Scheme 1:
The general structure of triazolylcalix[4]arene derivatives.
Beilstein J. Org. Chem.2018,14, 747–755, doi:10.3762/bjoc.14.63
this probe to include complementary base-pairing interactions. The theoretical calculations revealed the availability of multiple complex structures. The synthesis was performed using click chemistry and the nucleotiderecognition properties of the probe were evaluated using fluorescence spectroscopy
; nucleotiderecognition; Introduction
Nucleotides play essential roles in various physiological processes, such as energy transportation [1], DNA synthesis [2] and cell signaling events [3]. Especially, adenosine-5’-triphosphate (ATP) is vital, since it is the main energy source in living systems [4]. The
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Graphical Abstract
Figure 1:
Structures of the studied hydroxyflavone derivatives.